Why the study?
Does vitamin C improve angiotensin II-attenuated endothelium-dependent vasodilation in healthy young men?
Does vitamin C improve angiotensin II-attenuated endothelium-dependent vasodilation in healthy young men?
Vitamin C abolishes angiotensin II-induced attenuation of endothelium-dependent vasodilation in human forearm vessels, suggesting the impairment is mediated by superoxide anion production.
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Vitamin C may acutely restore Ang II-impaired endothelial function in healthy men; hypothesis-generating for superoxide-mediated mechanisms, should not change practice.
Hirooka et al. (2003) studied this question.
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