Why the study?
Does maintaining plasma Angiotensin II levels attenuate water immersion-induced natriuresis in healthy young males?
Population
15-18 healthy young males (8 in protocol 1, 7-10 in protocol 2)
Comparison
Water immersion combined with Angiotensin II… vs Water immersion + placebo, and a seated time…
Follow-up
3 hours
Authors
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Ang II suppression mediates immersion natriuresis in healthy males; extends mechanistic insight but leaves open clinical relevance.
Does maintaining plasma Angiotensin II levels attenuate water immersion-induced natriuresis in healthy young males?
Suppression of Angiotensin II generation is a key mechanism driving water immersion-induced natriuresis in humans.
Schou et al. (2002) studied this question.
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