Why the study?
Does water immersion to the neck increase atrial natriuretic peptide release in humans?
Population
Normal hydrated human subjects
Comparison
Water immersion (WI) to the neck vs Prestudy levels (baseline)
Design
Review
Follow-up
up to 2-3 hours of immersion
Authors
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Supports water immersion as a physiological research model; leaves open clinical translation to volume management.
Does water immersion to the neck increase atrial natriuretic peptide release in humans?
Water immersion is an effective physiological model demonstrating that atrial distension significantly increases ANP release, which plays a key role in volume homeostasis and natriuresis.
Epstein et al. (2008) studied this question.
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