Why the study?
How do measures of 24-hour GH secretion differ between men with adult-onset GH deficiency and normal men?
Population
40 men, comprising 23 with adult-onset pituitary disease defined as GH-deficient, and 17 normal men.
Comparison
24-hour frequent venous sampling of GH and… vs Normal men undergoing the same 24-hour frequent…
Design
Cross-sectional
Follow-up
24 hours
Authors
Loading...
Supports pooled 24-h GH measurement for distinguishing adult-onset GHD; leaves open optimal thresholds and prospective validation.
How do measures of 24-hour GH secretion differ between men with adult-onset GH deficiency and normal men?
Pooled 24-hour GH levels measured by a highly sensitive chemiluminescence assay provide the best separation between normal men and those with adult-onset GH deficiency, despite some overlap in other measures.
Baum et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: