Population
13 developing human hearts, 5 normal adult hearts, and 10 hearts from patients undergoing cardiac…
Design
Other
Authors
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May raise circulating ANP in severe heart failure; leaves open ventricular conduction system as clinically relevant extra-atrial source.
The ventricular conduction system and failing ventricular myocardium are extra-atrial sites for atrial natriuretic peptide synthesis, which may contribute to raised circulating ANP levels in severe congestive heart disease.
Wharton et al. (1988) studied this question.
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