Population
anesthetized open-chest dog model
Comparison
Serotonin 200 µg/kg administered via various… vs Response before versus after elimination of…
Design
Preclinical
Authors
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Chemoreceptors mediate serotonin pressor effects in dogs; leaves open translation to human cardiovascular responses.
This preclinical study demonstrates that the systemic and pulmonary pressor responses to high-dose serotonin in dogs are partially mediated by aortic and carotid chemoreceptors.
Braun et al. (1961) studied this question.
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