Population
Bovine pulmonary arterial endothelium in culture and vascular, tracheal, gastrointestinal, and uterine…
Comparison
Endothelium-derived relaxing factor released… vs Nitric oxide (NO)
Design
Preclinical
Authors
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EDRF shows vascular selectivity unlike NO; animal data leave open distinct endothelial mediators in human vascular control.
This study demonstrates a differential selectivity between the relaxant effects of EDRF and NO on various types of smooth muscle, suggesting they may have distinct physiological profiles.
Shikano et al. (1987) studied this question.
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