Why the study?
What are the pharmacokinetic and pharmacodynamic properties of amlodipine in the treatment of hypertension and angina pectoris?
Population
Patients with hypertension and angina pectoris
Design
Review
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Supports once-daily hypertension regimens; leaves open prospective outcome trials in angina pectoris.
What are the pharmacokinetic and pharmacodynamic properties of amlodipine in the treatment of hypertension and angina pectoris?
Amlodipine's long half-life and gradual onset of action provide sustained 24-hour blood pressure control with once-daily dosing and minimal reflex tachycardia.
A 2008 study studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: