Atrial Natriuretic Factor-induced Egression of Cyclic Guanosine 3′:5′-Monophosphate in Cultured Vascular Smooth Muscle and Endothelial Cells
Population
Cultured vascular smooth muscle and endothelial cells
Design
Preclinical
Follow-up
up to 24 h
Authors
Discussion
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Overview
May control vascular cell cGMP levels; leaves open human translation and therapeutic targeting.
Structured PICO
P
Population
Cultured vascular smooth muscle and endothelial cells
I
Intervention
Atrial natriuretic factor
O
Outcome
Characteristics of cyclic GMP egression to the extracellular fluidsurrogate
The egression of cyclic GMP from vascular cells is an active, regulated transport process that may significantly contribute to controlling intracellular cyclic GMP levels.
Cite This Study
Hamet et al. (1989) studied this question.