July 1, 1987The Journal of Clinical Endocrinology & Metabolism

Significance of Hepatic Triglyceride Lipase Activity in the Regulation of Serum High Density Lipoproteins in Type II Diabetes Mellitus*

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Population

30 patients with type II diabetes mellitus, selected to represent a wide range of serum HDL cholesterol…

Design

Cross-sectional

Authors

SKSidika E. KasimUniversity of Southern California KTKingston H. TsengPacific Medical (China)KJK.‐L. Catherine JenWayne State University

Discussion

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Implication

HTGL differences may contribute to HDL variation in T2DM; hypothesis-generating and leaves causal role open for prospective study.

Structured PICO

Population

30 patients with type II diabetes mellitus, selected to represent a wide range of serum HDL cholesterol concentrations (low, normal, and high HDL groups).

Outcome

Lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL) activities in plasma after iv injection of heparinsurrogate

In patients with type II diabetes mellitus, low serum HDL cholesterol levels may be driven by an increased rate of clearance by hepatic triglyceride lipase.

Cite This Study

Kasim et al. (1987) studied this question.

synapsesocial.com/papers/6a82c318e01a8b86dc13320e https://doi.org/10.1210/jcem-65-1-183

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Significance of Hepatic Triglyceride Lipase Activity in the Regulation of Serum High Density Lipoproteins in Type II Diabetes Mellitus*

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Significance of Hepatic Triglyceride Lipase Activity in the Regulation of Serum High Density Lipoproteins in Type II Diabetes Mellitus*

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider