Why the study?
Does long-term treatment with large oral dosage of propranolol change the early insulin response to intravenous glucose in patients with primary hypertension?
Does long-term treatment with large oral dosage of propranolol change the early insulin response to intravenous glucose in patients with primary hypertension?
Long-term treatment with large oral doses of propranolol does not appear to affect early insulin secretion in patients with primary hypertension.
Reassures on early insulin response with propranolol in hypertension; leaves open confirmation in randomized trials.
The early insulin response to i.v. glucose has been studied in 10 patients with primary hypertension before and during long‐term treatment with large oral dosage of propranolol. No change in the early insulin secretion was found.
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Hedstrand et al. (1974) studied this question.
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