Population
Mouse urinary bladder smooth muscle cells (UBSMCs) and tissue segments
Comparison
Depolarization of varying durations, application… vs Baseline conditions or shorter depolarizations
Design
Preclinical
Authors
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Challenges VDCC-centric Ca2+ model in bladder myocytes; leaves open human EC coupling relevance and therapeutic translation.
In mouse urinary bladder myocytes, excitation-contraction coupling relies primarily on a two-step calcium-induced calcium release rather than direct calcium influx through voltage-dependent channels.
Morimura et al. (2005) studied this question.
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