Population
Mouse models (intestine, stomach, uterus, bladder, aorta, heart vessels, lung) and 293T cells
Design
Preclinical
Authors
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mCLCA4 may serve as a smooth muscle chloride channel; leaves open its relevance to cystic fibrosis, cancer, and asthma.
Identifies mCLCA4 as a calcium-activated chloride channel expressed in smooth muscle, linking it to a gene family implicated in cystic fibrosis, cancer, and asthma.
Elble et al. (2002) studied this question.
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