Population
Intact and skinned smooth muscle of the rabbit mesenteric artery
Design
Preclinical
Authors
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Should not change clinical vascular management; hypothesis-generating for distinct Ca2+ stores in smooth muscle, pending human validation.
This study demonstrates that norepinephrine- and caffeine-sensitive calcium stores in vascular smooth muscle are distinct, with norepinephrine potentially triggering calcium-induced calcium release from the sarcoplasmic reticulum.
Saida et al. (2008) studied this question.
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