Key result
Milan normotensive rats exhibit an impaired myogenic response of the afferent arteriole compared to Milan hypertensive rats, contributing to increased susceptibility to renal disease.
Impaired myogenic response of the afferent arteriole in Milan normotensive rats leads to increased transmission of pressure to the glomerulus, contributing to their increased susceptibility to renal disease.
No takes yet. Share an insight, caveat, or question.
Impaired afferent arteriole myogenic response may promote glomerular injury in normotensive models; leaves open human translation.
Ge et al. (2017) studied Renal disease susceptibility. Milan normotensive (MNS) strain vs. Milan hypertensive (MHS) strain was evaluated on Myogenic response of isolated perfused afferent arterioles. Milan normotensive rats exhibit an impaired myogenic response of the afferent arteriole compared to Milan hypertensive rats, contributing to increased susceptibility to renal disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: