Why the study?
Do plasma and urinary endothelin-1 levels differ between salt-sensitive and salt-resistant hypertensive men across varying NaCl diets?
Do plasma and urinary endothelin-1 levels differ between salt-sensitive and salt-resistant hypertensive men across varying NaCl diets?
Salt-sensitive hypertension is associated with elevated plasma and urinary endothelin-1 levels, suggesting a potential mechanism for increased cardiovascular and renal risk.
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May mark salt-sensitive hypertension risk; leaves open whether endothelin-1 is a modifiable target.
Ferri et al. (1997) studied this question.
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