Key result
Mild renal dysfunction was more prevalent in stable angina patients under 60 with coronary artery disease compared to those with normal angiography.
Why the study?
The study investigated the relationship between mild renal dysfunction and the presence of coronary artery disease in individuals under 60 years of age.
Is mild renal dysfunction associated with an increased risk of coronary artery disease in young patients with stable angina pectoris?
Case-Control (n=634)
Is mild renal dysfunction associated with an increased risk of coronary artery disease in young patients with stable angina pectoris?
Lower eGFR and mild renal dysfunction are independent risk factors for the presence of coronary artery disease in patients under 60 years of age with stable angina.
Answers are grounded in this paper and cite their sources.
Mild renal dysfunction was associated with CAD in young stable angina; hypothesis-generating, prospective studies needed before clinical adoption.
Aim: We investigated the relationship between mild renal dysfunction (MRD) and the presence of coronary artery disease (CAD) in people under 60 years of age. Materials & methods: A total of 634 (317 patients with vessel stenosis ≥50% and 317 with normal angiography) individuals diagnosed with stable angina pectoris and estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73 m2 were included in the present study. Results: The mean eGFR was lower (95.3 ± 23.7 vs 109.7 ± 22.3, respectively, p = 0.002) and the number of patients with MRD was higher in patients with CAD (137, 43.2%) than in the control group (52, 16.4%, p < 0.001). The multivariate analysis showed that lower eGFR is an independent risk factor for presence of CAD in people under 60 years of age with stable angina pectoris. Conclusion: According to our retrospective study, the risk of developing CAD appears to be slightly increased in individuals under 60 years of age with MRD.
No takes yet. Share an insight, caveat, or question.
Duran et al. (2020) conducted a case-control in Stable angina pectoris (n=634). Coronary artery disease (vessel stenosis ≥50%) vs. Normal angiography was evaluated on Mild renal dysfunction (p=<0.001). Mild renal dysfunction was more prevalent in stable angina patients under 60 with coronary artery disease compared to those with normal angiography.
Synapse has enriched 10 related papers. Consider them for comparative context: