Why the study?
Is mild renal dysfunction associated with increased renal vascular resistance in patients with untreated primary hypertension?
Population
291 untreated patients with primary hypertension
Design
Cross-sectional
Authors
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May flag vascular resistance in untreated hypertension; hypothesis-generating, needs prospective validation before practice change.
Is mild renal dysfunction associated with increased renal vascular resistance in patients with untreated primary hypertension?
In untreated primary hypertension, increased renal vascular resistance is independently associated with a twofold higher risk of mild renal dysfunction.
Derchi et al. (2005) studied this question.
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