Why the study?
Does the use of estimated creatinine clearance or 24-hour urine collection increase the detected prevalence of mild chronic renal insufficiency compared to serum creatinine alone in patients with essential hypertension?
Population
2686 patients with essential hypertension referred to a single unit between 1979 and 1999
Comparison
Estimation of creatinine clearance by… vs Serum creatinine levels alone
Design
Cross-sectional
Authors
Loading...
Serum creatinine may underestimate MCRI prevalence in hypertension; hypothesis-generating for clearance-based assessment in prospective studies.
Does the use of estimated creatinine clearance or 24-hour urine collection increase the detected prevalence of mild chronic renal insufficiency compared to serum creatinine alone in patients with essential hypertension?
Mild chronic renal insufficiency is significantly underdiagnosed in essential hypertension when relying solely on serum creatinine rather than estimated creatinine clearance.
Segura et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: