October 9, 1981Science

Sodium Appetite in Sheep Induced by Cerebral Ventricular Infusion of Angiotensin: Comparison with Sodium Deficiency

View Full Paper

Ask AI

Bookmark

Structured PICO

Population

Sheep (including sodium-deficient sheep)

Intervention

Intraventricular administration of supraphysiological amounts of renin, nerve growth factor preparation, or angiotensin II, and angiotensin-blocking drugs

Outcome

Consumption of water and hypertonic sodium bicarbonate solution (sodium intake)surrogate

Central angiotensin action does not appear to be involved in sodium appetite due to sodium deficiency in sheep.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Central angiotensin blockade does not alter sodium appetite in deficient sheep; leaves open species-specific mechanisms in humans.

Cite This Study

Coghlan et al. (1981) studied this question.

synapsesocial.com/papers/6a831ab9f2457b8164efea66 https://doi.org/10.1126/science.6169149

View Full Paper

Ask AI

Bookmark