Why the study?
Does insulin infusion suppress in vivo skeletal muscle lipolysis in nonobese women?
Population
10 nonobese women
Comparison
Two-step euglycemic hyperinsulinemic clamp vs Basal state (pre-infusion)
Authors
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Insulin does not suppress skeletal muscle lipolysis in nonobese women; leaves open tissue-specific regulation and requires confirmation before clinical translation.
Does insulin infusion suppress in vivo skeletal muscle lipolysis in nonobese women?
Insulin does not inhibit the rate of lipolysis in skeletal muscle of nonobese women, unlike its marked suppressive effect in adipose tissue.
Moberg et al. (2002) studied this question.
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