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June 22, 2012PLoS ONEOpen Access

Differential Seroprevalence of Human Bocavirus Species 1-4 in Beijing, China

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Population

386 healthy individuals aged 0-70 years and 31 children with acute lower respiratory tract infections…

Design

Cross-sectional

Follow-up

2 weeks for the acute infection cohort

Authors

LGLi GuoIntelligent Health (United Kingdom)YWYaying WangChinese Academy of Medical Sciences & Peking Union Medical CollegeHZHongli ZhouInstitute of Chemical Technology

Discussion

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Implication

Supports HBoV1 surveillance in China; leaves open species-specific disease associations pending prospective studies.

Structured PICO

P
Population
386 healthy individuals aged 0-70 years (244 children aged 0-14 years, 142 adults aged ≥15 years) and 31 children (median age 17 months) with acute lower respiratory tract infections positive for HBoV1, in Beijing, China.
O
Outcome
Seroprevalence of specific anti-VP2 IgG antibodies against HBoV1-4surrogate

HBoV1 is the most prevalent human bocavirus species in Beijing, China, with seroprevalence increasing with age and significant cross-reactivity observed among HBoV species.

Cite This Study

Guo et al. (2012) studied this question.

synapsesocial.com/papers/6a832a7b4e20a508b1f46c69https://doi.org/10.1371/journal.pone.0039644
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  5. 5Human Bocavirus Infection in Children with Acute Gastroenteritis and Healthy Controls2008 · 46 citations