Why the study?
Does sickle cell trait carrier status alter nocturnal autonomic nervous system activity compared to healthy controls?
Does sickle cell trait carrier status alter nocturnal autonomic nervous system activity compared to healthy controls?
Sickle cell trait carriers exhibit an autonomic imbalance characterized by lowered parasympathetic activity and a sympathetic shift, which may represent an additional risk factor for cardiac complications.
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May signal added cardiac vulnerability in SCT; hypothesis-generating for prospective arrhythmia risk studies.
Connes et al. (2006) studied this question.
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