Why the study?
Does heparin-dihydergot reduce the incidence of deep-vein thrombosis compared to heparin-acenocoumarin in women undergoing Ender nailing for intertrochanteric fracture of the femur?
Does heparin-dihydergot reduce the incidence of deep-vein thrombosis compared to heparin-acenocoumarin in women undergoing Ender nailing for intertrochanteric fracture of the femur?
Heparin-dihydergot significantly reduced the incidence of deep-vein thrombosis compared to heparin-acenocoumarin in women undergoing surgery for intertrochanteric femur fractures.
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Heparin-dihydergot was associated with fewer DVTs after Ender nailing; leaves open optimal prophylaxis pending randomized trials.
The effect of either heparin-dihydergot or heparin-acenocoumarin on the incidence of deep-vein thrombosis in the legs was studied in 181 women undergoing Ender nailing for intertrochanteric fracture of the femur. All the patients were screened with the 125-I-fibrinogen uptake test, confirmed by a bilateral ascending venogram. Deep-vein thrombosis developed in 40 per cent of the heparin-dihydergot group and in 61 per cent of the heparin-acenocoumarin group (p less than 0.015).
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Schlag et al. (1986) studied this question.
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