Why the study?
Does injection of thermosensitive Dex-PCL-HEMA/PNIPAAm hydrogel prevent adverse cardiac remodelling and dysfunction in rabbits with induced myocardial infarction?
Does injection of thermosensitive Dex-PCL-HEMA/PNIPAAm hydrogel prevent adverse cardiac remodelling and dysfunction in rabbits with induced myocardial infarction?
Implantation of a novel thermosensitive hydrogel into infarcted myocardium prevents adverse cardiac remodelling and improves cardiac function in a preclinical rabbit model.
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Warrants further preclinical testing of injectable hydrogels post-MI; leaves open safety and efficacy in humans.
Wang et al. (2009) studied this question.
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