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March 22, 2012Arthritis Care & ResearchOpen Access

Using exercise training to counterbalance chronotropic incompetence and delayed heart rate recovery in systemic lupus erythematosus: A randomized trial

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Why the study?

Does a 3-month exercise training program improve chronotropic reserve and heart rate recovery in inactive patients with systemic lupus erythematosus?

Population

Inactive patients with systemic lupus erythematosus and sex-, body mass index-, and age-matched healthy…

Comparison

3-month (12-week) exercise training program vs Nontrained (NT) group

Design

RCT, Randomly assigned

Follow-up

12 weeks

Authors

RMRenata MiossiFBFabiana Braga BenattiAPAna Lúciade de Sá Pinto

Discussion

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Member takes

Overview

Supports exercise training for autonomic dysfunction in inactive SLE; extends RCT evidence to this high-CV-risk population.

Structured PICO

Does a 3-month exercise training program improve chronotropic reserve and heart rate recovery in inactive patients with systemic lupus erythematosus?

P
Population
Inactive patients with systemic lupus erythematosus (SLE) (stated as n=24, but groups listed as trained n=15 and nontrained n=13) and sex-, body mass index-, and age-matched healthy controls (n=8).
I
Intervention
3-month (12-week) exercise training program
C
Comparator
Nontrained (NT) group
O
Outcome
Chronotropic reserve (CR) and heart rate (HR) recovery at the first (ΔHRR1) and second (ΔHRR2) minutes after peak exercise at 12 weekssurrogate

A 12-week exercise training program safely improves chronotropic incompetence and delayed heart rate recovery in physically inactive patients with systemic lupus erythematosus.

Cite This Study

Miossi et al. (2012) studied this question.

synapsesocial.com/papers/6a8365850609b3655ee4e665https://doi.org/10.1002/acr.21678
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abnormal chronotropic reserve and heart rate recovery in patients with SLE: a case–control study2011 · 24 citations
  2. 2Attenuated post-exercise heart rate recovery in patients with systemic lupus erythematosus: the role of disease severity and beta-blocker treatment2017 · 10 citations
  3. 3Deterioration of Heart Rate Recovery Index in Patients with Systemic Lupus Erythematosus2010 · 25 citations
  4. 4P151 ActiLup – High intensity interval training and fatigue in systemic lupus erythematosus2024 · 2 citations
  5. 5Exercise training responses in lupus-prone MRL-lpr mice2026