Why the study?
Does systemic lupus erythematosus impair post-exercise heart rate recovery compared to healthy controls?
Population
55 patients with systemic lupus erythematosus without coronary artery disease, diabetes mellitus, or…
Comparison
Systemic lupus erythematosus (disease state) vs Healthy controls
Design
Case-control
Key result
Patients with systemic lupus erythematosus had significantly attenuated heart rate recovery at 1 minute post-exercise compared to healthy controls (36.9 vs 49.5, p=0.0004).
Authors
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Suggests cardiac autonomic dysfunction may be an underrecognized cardiovascular risk factor in systemic.
Observational (n=85)
Does systemic lupus erythematosus impair post-exercise heart rate recovery compared to healthy controls?
Absolute Event Rate: 36.9% vs 49.5%
p-value: p=0.0004
Patients with SLE exhibit attenuated post-exercise heart rate recovery, which correlates with disease severity and beta-blocker use, suggesting cardiac autonomic dysfunction.
Bienias et al. (2017) conducted an observational in Systemic lupus erythematosus (n=85). Systemic lupus erythematosus vs. Healthy controls was evaluated on Heart rate recovery at the first minute of rest (HRR1) (p=0.0004). Patients with systemic lupus erythematosus had significantly attenuated heart rate recovery at 1 minute post-exercise compared to healthy controls (36.9 vs 49.5, p=0.0004).
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