Why the study?
Does aging alter the cardiovascular control by the chemoreflex and baroreflex in rats?
Population
Old rats (24 months) and young rats (4 months)
Comparison
Chemoreflex activation with increasing doses of… vs Young rats (4 months)
Design
Preclinical
Authors
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Exaggerated chemoreflex bradycardia in aged rats should not change human practice; leaves open translational relevance for age-related autonomic dysfunction.
Does aging alter the cardiovascular control by the chemoreflex and baroreflex in rats?
Aging in rats is associated with exaggerated bradycardia and pressor responses to chemoreflex activation, but depressed heart rate responses to baroreflex activation.
Franchini et al. (1996) studied this question.
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