This review summarizes current literature on how muscle afferents regulate cardiovascular responses to exercise in cardiomyopathy.
Synthesizes evidence on muscle afferent control of exercise responses in cardiomyopathy; leaves open prospective trials before clinical translation.
In Brief Abnormal cardiovascular responses to exercise in heart failure contribute significantly to the morbidity and mortality in the patient population. These abnormal responses may be the result of peripheral impairment in the skeletal muscle and the neurons that innervate the muscle. We present the current literature on the role of muscle afferents in regulating the cardiovascular responses to exercise in cardiomyopathy. This article reviews the current literature on the role of muscle afferents in regulating the cardiovascular responses to exercise in cardiomyopathy.
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Mary G. Garry (2011) studied this question.
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