Why the study?
Does prothrombin time correlate with plasma rivaroxaban levels in patients receiving rivaroxaban therapy?
Does prothrombin time correlate with plasma rivaroxaban levels in patients receiving rivaroxaban therapy?
A normal prothrombin time measured by Recombiplastin 2G strongly correlates with low rivaroxaban levels and may exclude therapeutic anticoagulation, potentially inferring suitability for surgery when specific anti-Xa assays are unavailable.
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PT may correlate with rivaroxaban levels in cross-sectional data; leaves open utility for perioperative decisions without anti-Xa assays.
Rodgers et al. (2013) studied this question.
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