Why the study?
The impact of coronary stent design on deformation, strut obstruction at a jailed side branch ostium, and malapposition during the POT-PBED sequence was unknown.
Does a 3-link stent design reduce stent strut malapposition compared to a 2-link stent design during bifurcation PCI using the POT-PBED sequence in bench models?
Does a 3-link stent design reduce stent strut malapposition compared to a 2-link stent design during bifurcation PCI using the POT-PBED sequence in bench models?
In a bench model of bifurcation PCI using the POT-PBED sequence, 3-link stents significantly reduced stent strut malapposition compared to 2-link stents without compromising side branch access.
Bench data on POT-PBED and stent design effects warrant clinical validation; leaves optimal device selection open.
The proximal optimizing technique (POT) -proximal balloon edge dilation (PBED) sequence for side branch (SB) dilatation with cross-over single-stent implantation decreases both strut obstruction at the SB ostium and stent deformation at the main branch (MB).The purpose of this experimental bench test was to assess the impact of stent design on stent deformation, obstruction by stent struts at a jailed SB ostium, and stent strut malapposition in the POT-PBED sequence.Fractal coronary bifurcation bench models (60- and 80-degree angles) were used, and crossover single-stent implantation (3-link stent: XIENCE Sierra, Abbott Vascular, Santa Clara, CA, n = 10; 2-link stent: Synergy, Boston Scientific, Marlborough, MA, n = 10) was performed from the MB using the POT-PBED sequence. Jailing rates at the SB ostium, stent deformation, and stent strut malapposition of the bifurcation segment were assessed using videoscopy and optical coherence tomography.After SB dilatation using the PBED technique, jailing rates at the SB ostium and stent deformation did not differ significantly between the two types of stents. Conversely, the rate of malapposed struts of the bifurcation segment after the PBED procedure was significantly lower with 3-link stents than with 2-link stents for both 60- and 80-degree angles (60-degree angle: 4.3% ± 4.4% versus 22.0% ± 11.1%, P = 0.044; 80-degree angle: 20.8% ± 15.1% versus 57.2% ± 17.0%, P < 0.001, respectively).In the POT-PBED sequence, 3-link stents might be a preferable coronary bifurcation stent, maintaining a jailed SB ostium while significantly reducing stent strut malapposition of the bifurcation segment when compared with 2-link stents.
No takes yet. Share an insight, caveat, or question.
Kume et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: