January 26, 2006Acta Physiologica

An investigation into the physiological relevance of the vagal tachycardia in the anaesthetized dog

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Population

Anaesthetized dogs

Comparison

Vagal section or atropine administration during… vs Intrinsic heart rate

Design

Preclinical

Authors

FMF. MarkosUniversity College Cork HSH. M. SnowUniversity College Cork

Discussion

Member takes

Implication

Questions physiological role of vagal tachycardia in vivo; animal data leave open relevance to human heart rate control.

Structured PICO

Population

Anaesthetized dogs

Intervention

Vagal section or atropine administration (9-20 microg kg-1) during high vagal activity induced by noradrenaline infusion (20 microg min-1), in the presence of atenolol (2 mg kg-1)

Comparator

Intrinsic heart rate

Outcome

Change in heart rate (magnitude of tachycardia)surrogate

Vagal tachycardia cannot be elicited without atropine in vivo, suggesting it does not play a significant physiological role.

Cite This Study

Markos et al. (2006) studied this question.

synapsesocial.com/papers/6a83d486448cdc0007ee8247 https://doi.org/10.1111/j.1748-1716.2006.01524.x

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Bookmark

An investigation into the physiological relevance of the vagal tachycardia in the anaesthetized dog

Discussion

Member takes

Implication

Structured PICO

Cite This Study

An investigation into the physiological relevance of the vagal tachycardia in the anaesthetized dog

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider