Population
Human embryonic stem cell-derived cardiomyocytes (hESC-CMs)
Comparison
Differentiation via END-2 co-culture or… vs Comparison between differentiation methods…
Design
Preclinical
Authors
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Supports hESC-CM exploration for in vitro testing; leaves open optimization of differentiation for consistent maturity.
hESC-CMs display heterogeneous but partially mature electrical phenotypes, demonstrating potential utility for pharmaceutical testing while highlighting the need for improved differentiation methods.
Pekkanen-Mattila et al. (2010) studied this question.
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