Why the study?
Does oral Prostaglandin E2 induce successful vaginal delivery in patients at or near term?
Does oral Prostaglandin E2 induce successful vaginal delivery in patients at or near term?
Oral Prostaglandin E2 is effective for inducing labour at or near term, resulting in successful vaginal delivery in over 80% of patients.
Answers are grounded in this paper and cite their sources.
May support oral PGE2 for labor induction in this cohort; hypothesis-generating and requires randomized trials before practice change.
Prostaglandin E2 (PgE2) tablets were administered orally for the induction of labour at or near term to 680 patients. Successful vaginal delivery occurred in 81.8% of patients with a mean total dose of 3.7 mg and a mean induction-delivery interval of 7.1 hours. PgE2 was most efficacious in parous patients and in those with high Bishop scores. The most common maternal side-effects were gastro-intestinal in nature and uterine hypertonus was observed in six patients. Foetal heart rate changes occurred in fifty patients.
No takes yet. Share an insight, caveat, or question.
Squires et al. (1980) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: