DHRS7c is a novel endo/sarcoplasmic reticulum-localized short chain dehydrogenase/reductase whose expression is inversely correlated with adrenergic stimulation and heart failure development.
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DHRS7c downregulation marks adrenergic stress across HF models; leaves open its causal role and therapeutic potential in humans.
Lü et al. (2011) studied this question.
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