Population
21 echoviruses, 8 coxsackieviruses, and poliovirus strains
Comparison
Increased concentrations of MgCl2, l-cysteine… vs Cationic and anionic polymers or standard medium
Design
Preclinical
Authors
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May aid enterovirus quantification in lab settings; leaves open translation to clinical diagnostics or enteroviral disease research.
The addition of MgCl2, cysteine, or pancreatin to agar overlay medium enhances plaque formation, allowing for effective quantification of enteroviruses that are otherwise difficult to assay.
Wallis et al. (1966) studied this question.