Why the study?
Does rapamycin improve allograft survival in rat models of ongoing and accelerated rejection?
Does rapamycin improve allograft survival in rat models of ongoing and accelerated rejection?
Rapamycin significantly prolongs allograft survival and reverses ongoing rejection in rat models of heart, kidney, and pancreas transplantation.
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Supports rapamycin in rodent allograft models; leaves open translation to human rejection prevention.
Chen et al. (1993) studied this question.
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