Why the study?
How rapidly does platelet function recover after cessation of aspirin therapy in healthy volunteers and surgical patients?
Population
72 individuals, comprising 14 healthy male volunteers and 58 aspirin-treated patients scheduled for elective…
Comparison
Cessation of aspirin therapy. vs Baseline platelet function during aspirin…
Design
Cohort
Follow-up
Up to 10 days after drug cessation
Authors
Loading...
May support shorter preoperative aspirin discontinuation in select patients; leaves open confirmation in randomized trials of bleeding outcomes.
How rapidly does platelet function recover after cessation of aspirin therapy in healthy volunteers and surgical patients?
Platelet function recovers within 4-6 days after aspirin cessation in most patients, suggesting that the standard preoperative waiting period may be individualized and potentially shortened.
Zisman et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: