Why the study?
Does ischemic preconditioning cause protein kinase C translocation in rabbit hearts?
Population
Rabbit ischemia model (rabbit hearts)
Comparison
Ischemic preconditioning vs Time-matched, sham-operated animals, and/or 10…
Design
Preclinical
Authors
Loading...
PKC translocation does not mediate preconditioning in this rabbit model; challenges prior hypotheses and leaves open its role in other species.
Does ischemic preconditioning cause protein kinase C translocation in rabbit hearts?
Direct biochemical measurements indicate that translocation of protein kinase C is not an important mediator of ischemic preconditioning in the rabbit ischemia model.
Simkhovich et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: