Key result
In vitro 3D model bench testing altered the treatment strategy in all 15 patients and led to the selection of significantly smaller Venus P-valves compared to conventional balloon sizing (median 32 mm vs 36 mm, P<0.001).
Why the study?
Due to wide variations in morphology, size, and dynamics, selecting optimal valve size and location poses great difficulty in percutaneous pulmonary valve implantation.
Does in vitro bench testing using patient-specific 3D models improve valve size selection and procedural planning in patients undergoing percutaneous pulmonary valve implantation?
Population
15 patients scheduled to undergo PPVI
Comparison
In vitro bench testing using patient-specific 3D-printed models vs conventional planning
Design
Single-center observational study
Authors
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May support 3D modeling over balloon sizing for P-valve selection; leaves open whether smaller valves improve clinical outcomes.
Observational (n=15)
No
Does in vitro bench testing using patient-specific 3D models improve valve size selection and procedural planning in patients undergoing percutaneous pulmonary valve implantation?
Absolute Event Rate: 32% vs 36%
p-value: p=<0.001
Patient-specific 3D-printed models for PPVI planning safely reduced the need for significant valve oversizing compared to conventional balloon-sizing techniques, optimizing procedural success.
Han et al. (2023) conducted an observational in Dilated right ventricular outflow tract and chronic severe pulmonary regurgitation (n=15). 3D model bench testing for PPVI planning vs. Conventional planning (balloon sizing) was evaluated on Venus P-valve diameter selection (p=<0.001). In vitro 3D model bench testing altered the treatment strategy in all 15 patients and led to the selection of significantly smaller Venus P-valves compared to conventional balloon sizing (median 32 mm vs 36 mm, P<0.001).
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