Why the study?
Does prinodolol compared to propranolol improve hyperthyroid tachycardia?
Does prinodolol compared to propranolol improve hyperthyroid tachycardia?
Prinodolol is less effective than propranolol for managing hyperthyroid tachycardia, likely due to its intrinsic sympathomimetic activity.
Answers are grounded in this paper and cite their sources.
May favor propranolol over prinodolol for hyperthyroid tachycardia; leaves open confirmation in randomized trials.
Summary LB 46 (prinodolol) a β-adrenergic receptor blocking drug which is more potent than propranolol in euthyroid subjects, is less effective in inhibiting hyperthyroid tachycardia. This is probably due to its intrinsic sympathomimetic activity.
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Arbab et al. (1971) studied this question.
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