Why the study?
Do single oral doses of propranolol, practolol, and metoprolol reduce exercise-induced tachycardia in normal volunteers?
Population
6 normal volunteers
Comparison
Single oral doses of propranolol, practolol, or… vs Control conditions
Design
Other
Follow-up
1.5 to 2 hours after drug ingestion
Authors
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Supports similar acute beta-blockade in healthy volunteers; leaves open differential effects or outcomes in patients.
Do single oral doses of propranolol, practolol, and metoprolol reduce exercise-induced tachycardia in normal volunteers?
Metoprolol is a potent short-acting cardioselective beta-blocker that effectively reduces exercise-induced tachycardia similarly to propranolol and practolol.
Williams et al. (1976) studied this question.
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