Population
Rat aortic smooth muscle cells (VSMCs) in primary culture
Comparison
8-bromo-cGMP or atrial natriuretic peptide vs Untreated cells (implied)
Design
Preclinical
Authors
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cGMP may regulate VSMC calcium via Na+/Ca2+ exchange; leaves open translation to vascular function or therapy.
cGMP stimulates Na+/Ca2+ exchange in vascular smooth muscle cells, providing insight into cellular calcium regulation mechanisms.
Furukawa et al. (1991) studied this question.
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