Key result
Chronic exercise training induces alterations in cardiac myocyte contractile properties, including increased Ca2+ sensitivity, altered force-length relationship, and increased power output.
Why the study?
Does chronic exercise training alter the contractile properties of cardiac myocytes?
Population
Cardiac myocytes (specifically "skinned" cardiac myocytes)
Design
Review
Authors
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May explain exercise benefits at cellular level; leaves open translation to human outcomes or therapies.
Does chronic exercise training alter the contractile properties of cardiac myocytes?
Chronic exercise training improves cardiac function at the cellular level by altering the contractile properties and myosin isoform expression of cardiac myocytes.
Gary M. Diffee (2004) conducted a review in Cardiac adaptation to exercise. Exercise training was evaluated on Contractile properties of cardiac myocytes. Chronic exercise training induces alterations in cardiac myocyte contractile properties, including increased Ca2+ sensitivity, altered force-length relationship, and increased power output.
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