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May 6, 2025Thrombosis UpdateOpen Access

Developing a decision support tool for the continuation or deprescribing of antithrombotic therapy in patients receiving end-of-life care: Protocol for a European Delphi study

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Why the study?

A consensus process was needed to inform the development of a European shared decision support tool regarding the continuation or deprescribing of antithrombotic therapy in cancer patients at the end of life.

Population

Representative expert panel of physicians, pharmacists, nurses, and psychologists from eight European countries

Design

Three-round European Delphi study protocol

Authors

IDImène DenecheInstitut Gustave RoussyCCCamille CouffignalUniversité Claude Bernard Lyon 1AHAnette Arbjerg HøjenAalborg University Hospital

Discussion

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Member takes

Overview

May guide ATT decisions in cancer EOL care; leaves open practice change pending validation.

Structured PICO

P
Population
Cancer patients at the end of life receiving antithrombotic therapy (ATT)
I
Intervention
Shared decision support tool (SDST) for the continuation or deprescribing of antithrombotic therapy
O
Outcome
Consensus on aspects relating to the continuation or deprescribing of antithrombotic therapy (characterisation of candidate patients, healthcare team roles, information requirements, SDST content priorities, and optimal outcomes for planned clinical trial)

This protocol outlines a European Delphi study to develop a shared decision support tool for managing antithrombotic therapy in end-of-life cancer patients.

Cite This Study

Deneche et al. (2025) studied this question.

synapsesocial.com/papers/6a849fe007ef115f76387ceahttps://doi.org/10.1016/j.tru.2025.100209
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Epidemiology of cancer-associated venous thrombosis2013 · 1,219 citations
  2. 2Use of antithrombotics at the end of life: an in-depth chart review study2021 · 28 citations
  3. 3Management of venous thromboembolism in far-advanced cancer: current practice2019 · 30 citations
  4. 4Impact of Potentially Inappropriate Prescribing on Adverse Drug Events, Health Related Quality of Life and Emergency Hospital Attendance in Older People Attending General Practice: A Prospective Cohort Study2016 · 180 citations