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January 1, 2017Journal of Anesthesia & Clinical Research

Gabapentin as Premedication for Postoperative Analgesia in Children: A Prospective Randomized Controlled Study

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Why the study?

Does gabapentin reduce postoperative pain and analgesia consumption in children undergoing orthopedic surgery?

Population

n=80 children aged 10-12 years old scheduled for orthopedic surgery in upper and lower limbs

Comparison

Gabapentin 300 mg given orally 2 h before… vs Placebo given 2 h before induction of anesthesia

Design

RCT, Randomly allocated equally in two groups

Follow-up

24 hours postoperative

Authors

MMMona Mohamed MogahedMGMohamed Samir Abd El Ghaffar

Discussion

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Overview

Supports preoperative gabapentin to reduce postoperative analgesia needs after pediatric orthopedic surgery; extends RCT evidence for multimodal analgesia in children.

Structured PICO

Does gabapentin reduce postoperative pain and analgesia consumption in children undergoing orthopedic surgery?

P
Population
n=80 children aged 10-12 years old scheduled for orthopedic surgery in upper and lower limbs
I
Intervention
Gabapentin 300 mg given orally 2 h before induction of anesthesia
C
Comparator
Placebo given 2 h before induction of anesthesia
O
Outcome
Postoperative pain score and consumption of analgesiapatient reported

Preoperative administration of gabapentin significantly reduces postoperative pain and analgesia consumption in children undergoing orthopedic surgery.

Cite This Study

Mogahed et al. (2017) studied this question.

synapsesocial.com/papers/6a84abd9e541b496dfbcc346https://doi.org/10.4172/2155-6148.1000759
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Advances in Neuropathic Pain2003 · 1,215 citations
  2. 2Preoperative Gabapentin Decreases Anxiety and Improves Early Functional Recovery from Knee Surgery2005 · 259 citations
  3. 3Pain Intensity on the First Day after Surgery2013 · 1,584 citations
  4. 4A randomized controlled trial to compare pregabalin with gabapentin for postoperative pain in abdominal hysterectomy2011 · 91 citations
  5. 5A randomized double-blind placebo-controlled clinical study on the effects of gabapentin premedication on hemodynamic stability during laparoscopic cholecystectomy2012 · 18 citations