Key result
A single preoperative 600 mg dose of gabapentin significantly decreased postoperative pain scores at 6 and 12 hours compared to placebo in patients undergoing ambulatory anal surgeries.
Why the study?
Anal surgeries remain painful despite advances in pain management, and efficient postoperative pain control is essential for recovery, faster healing, mobilization, and shorter hospital stays.
Does a single preoperative dose of gabapentin reduce postoperative pain in patients undergoing ambulatory anal surgeries?
Population
50 patients undergoing ambulatory anal surgeries under spinal anesthesia
Comparison
Oral gabapentin 600 mg vs oral placebo tablet
Design
Prospective, randomized, double-blind controlled study
Follow-up
12h
Authors
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Supports preoperative gabapentin for early pain control after ambulatory anal surgery; extends RCT evidence to this specific outpatient setting.
RCT (n=50)
Double-blind
randomized
Does a single preoperative dose of gabapentin reduce postoperative pain in patients undergoing ambulatory anal surgeries?
A single preoperative 600 mg dose of gabapentin significantly reduces postoperative pain and opioid consumption in patients undergoing ambulatory anal surgeries.
Mousa et al. (2023) conducted an RCT in Ambulatory anal surgeries (n=50). Gabapentin vs. Placebo was evaluated on Severity of postoperative pain (visual analog scale 0 to 10 cm) at 0, 6, and 12h. A single preoperative 600 mg dose of gabapentin significantly decreased postoperative pain scores at 6 and 12 hours compared to placebo in patients undergoing ambulatory anal surgeries.
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