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June 25, 2013Expert Opinion on Pharmacotherapy

Loop diuretics and ultrafiltration in heart failure

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Why the study?

What is the efficacy and safety of loop diuretics and ultrafiltration in heart failure?

Population

Patients with congestive heart failure (HF) and acute decompensated HF

Design

Review

Authors

PRPatrick RossignolFZFaı̈ez Zannad

Discussion

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Overview

Highlights gaps in HF decongestion guidance; leaves open prospective validation of biomarker-based algorithms.

Structured PICO

What is the efficacy and safety of loop diuretics and ultrafiltration in heart failure?

P
Population
Patients with congestive heart failure (HF) and acute decompensated HF
I
Intervention
Loop diuretics and venous ultrafiltration
O
Outcome
Efficacy and safety

There is an unmet need for evidence-based algorithms incorporating biomarkers to optimize decongestion therapies in heart failure.

Cite This Study

Rossignol et al. (2013) studied this question.

synapsesocial.com/papers/6a84f729045f75bf5ef117cbhttps://doi.org/10.1517/14656566.2013.808332
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Loop Diuretic Therapy in Heart Failure: The Need for Solid Evidence on a Fluid Issue2010 · 49 citations
  2. 2Loop diuretics in acute heart failure: beyond the decongestive relief for the kidney2015 · 56 citations
  3. 3Diuretic Treatment in Patients with Heart Failure: Current Evidence and Future Directions – Part I: Loop Diuretics2024 · 45 citations
  4. 4Loop Diuretics Strategies in Acute Heart Failure: From Clinical Trials to Practical Application2015 · 3 citations
  5. 5Ultrafiltration in the management of heart failure2008 · 35 citations