Why the study?
Does a simplified thromboplastin calibration procedure using pooled lyophilized plasmas equal the standard procedure using individual freshly prepared plasmas for batch-to-batch control?
Does a simplified thromboplastin calibration procedure using pooled lyophilized plasmas equal the standard procedure using individual freshly prepared plasmas for batch-to-batch control?
A simplified thromboplastin calibration procedure using pooled lyophilized plasmas is equivalent to the standard method, potentially streamlining laboratory workflows for anticoagulant control.
May streamline Thrombotest calibration workflows; leaves open need for broader validation before routine adoption.
The modified (and thereby simplified) thromboplastin calibration procedure using pooled lyophilized normal and patient plasmas is shown to equal, for batch-to-batch control of Thrombotest, the calibration procedure described by Biggs and Denson, which makes use of individual freshly prepared patient plasmas.
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Besselaar et al. (1980) studied this question.
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