Population
Mice (immunized orally with live Sabin type 1 poliovirus in combination with cholera toxin)
Design
Preclinical
Authors
Loading...
Maps poliovirus IgA neutralization epitopes in a mouse model; leaves open translation to human mucosal vaccines or MAbs.
The study identifies specific neutralization epitopes on Sabin type 1 poliovirus recognized by mucosal IgA antibodies, including a novel mutation site in VP2.
Fiore et al. (1997) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: